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Improved Statistical Signal Detection in Pharmacovigilance by Combining Multiple Strength-of-Evidence Aspects in vigiRank: Retrospective Evaluation against Emerging Safety Signals

BACKGROUND: Detection of unknown risks with marketed medicines is key to securing the optimal care of individual patients and to reducing the societal burden from adverse drug reactions. Large collections of individual case reports remain the primary source of information and require effective analy...

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Detalhes bibliográficos
Main Authors: Caster, Ola, Juhlin, Kristina, Watson, Sarah, Norén, G. Niklas
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134478/
https://ncbi.nlm.nih.gov/pubmed/25052742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40264-014-0204-5
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