Increased Ang II Contraction of the Uterine Artery at Early Gestation in A Transgenic Model of Hypertensive Pregnancy is Reduced by Inhibition of Endocannabinoid Hydrolysis

Increased vascular sensitivity to Ang II is a marker of a hypertensive human pregnancy. Recent evidence of interactions between the RAS and the endocannabinoid system (ECS) suggests that anandamide (AEA) and 2-arachidonoylglycerol (2-AG) may modulate Ang II contraction. We hypothesized that these in...

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Hauptverfasser: Pulgar, Victor M., Yamaleyeva, Liliya M., Varagic, Jasmina, McGee, Carolynne M., Bader, Michael, Dechend, Ralf, Howlett, Allyn C., Brosnihan, K. Bridget
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134408/
https://ncbi.nlm.nih.gov/pubmed/24935942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03633
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