Local uterine Ang-(1–7) infusion augments the expression of cannabinoid receptors and differentially alters endocannabinoid metabolizing enzymes in the decidualized uterus of pseudopregnant rats

BACKGROUND: Endocannabinoids (ECs) are important contributors to implantation and decidualization and are suppressed in early pregnancy. Elevated levels of anandamide (AEA), the endogenous ligand for the CB1 and CB2 receptors (R), interfere with receptivity of the blastocyst. Ang-(1–7) is down-regul...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Reprod Biol Endocrinol
Main Authors: Brosnihan, K Bridget, Pulgar, Victor M, Gallagher, Patricia E, Neves, Liomar AA, Yamaleyeva, Liliya M
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325957/
https://ncbi.nlm.nih.gov/pubmed/25596750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-13-5
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