The cytoplasmic tail of lysosomal acid phosphatase contains overlapping but distinct signals for basolateral sorting and rapid internalization in polarized MDCK cells.

Lysosomal acid phosphatase (LAP) is synthesized as a type I membrane glycoprotein and targeted to lysosomes via the plasma membrane. Its cytoplasmic tail harbours a tyrosine-containing signal for rapid internalization. Expression in Madine-Darby canine kidney cells results in direct sorting to the b...

ver descrição completa

Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Prill, V, Lehmann, L, von Figura, K, Peters, C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413439/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8491206/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05866.x
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!