Epigenetic Inactivation of Inositol polyphosphate 4-phosphatase B (INPP4B), a Regulator of PI3K/AKT Signaling Pathway in EBV-Associated Nasopharyngeal Carcinoma

Nasopharyngeal carcinoma (NPC) is a common viral-associated neoplasm in which multiple signaling cascades are interfered with by Epstein-Bar virus (EBV) latent proteins and various genetic alterations. Aside from the previously reported PIK3CA amplification, we examined the role of INPP4B, a negativ...

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Main Authors: Yuen, Jessie Wai-Fong, Chung, Grace Tin-Yun, Lun, Samantha Wei-Man, Cheung, Chartia Ching-Mei, To, Ka-Fai, Lo, Kwok-Wai
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134277/
https://ncbi.nlm.nih.gov/pubmed/25126743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105163
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