Increased Expression of CCN2, Epithelial Membrane Antigen, and Fibroblast Activation Protein in Hepatocellular Carcinoma with Fibrous Stroma Showing Aggressive Behavior

Tumor behavior is affected by the tumor microenvironment, composed of cancer-associated fibroblasts (CAFs). Meanwhile, hepatocellular carcinomas (HCC) with fibrous stroma reportedly exhibit aggressive behavior suggestive of tumor-stroma interaction. However, evidence of the crosstalk remains unclear...

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Autori principali: Kim, Gi Jeong, Rhee, Hyungjin, Yoo, Jeong Eun, Ko, Jung Eun, Lee, Jee San, Kim, Hyunki, Choi, Jin Sub, Park, Young Nyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134271/
https://ncbi.nlm.nih.gov/pubmed/25126747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105094
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