Increased expression of stemness markers and altered tumor stroma in hepatocellular carcinoma under TACE-induced hypoxia: A biopsy and resection matched study

BACKGROUND: Hepatocellular carcinomas (HCCs) expressing stemness markers are characterized by an aggressive behavior, which might be promoted by an altered tumor stroma. Transarterial chemoembolization (TACE) induces severe hypoxia, and its effect on stemness and tumor stroma of HCCs remains unclear...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Nahm, Ji Hae, Rhee, Hyungjin, Kim, Haeryoung, Yoo, Jeong Eun, San Lee, Jee, Jeon, Youngsic, Choi, Gi Hong, Park, Young Nyun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725098/
https://ncbi.nlm.nih.gov/pubmed/29245907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22078
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