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In vivo characterization of a bigenic fluorescent mouse model of Alzheimer’s disease with neurodegeneration

The loss of cognitive function in Alzheimer’s disease (AD) patients is strongly correlated with the loss of neurons in various regions of the brain. We have created a new fluorescent bigenic mouse model of AD by crossing “H-line” yellow fluorescent protein (YFP) mice with the 5xFAD mouse model, whic...

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Detalhes bibliográficos
Main Authors: Crowe, Sarah E., Ellis-Davies, Graham C.R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134262/
https://ncbi.nlm.nih.gov/pubmed/23348594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23306
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