Inhibition of HMGB1-Induced Angiogenesis by Cilostazol via SIRT1 Activation in Synovial Fibroblasts from Rheumatoid Arthritis

High mobility group box chromosomal protein 1 (HMGB-1) released from injured cells plays an important role in the development of arthritis. This study investigated the anti-angiogenic effects of cilostazol in collagen-induced arthritis (CIA) of mice, and the underlying mechanisms involved. The expre...

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Main Authors: Kim, Hye Young, Park, So Youn, Lee, Sung Won, Lee, Hye Rin, Lee, Won Suk, Rhim, Byung Yong, Hong, Ki Whan, Kim, Chi Dae
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134224/
https://ncbi.nlm.nih.gov/pubmed/25126750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104743
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