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Inhibition of HMGB1-Induced Angiogenesis by Cilostazol via SIRT1 Activation in Synovial Fibroblasts from Rheumatoid Arthritis
High mobility group box chromosomal protein 1 (HMGB-1) released from injured cells plays an important role in the development of arthritis. This study investigated the anti-angiogenic effects of cilostazol in collagen-induced arthritis (CIA) of mice, and the underlying mechanisms involved. The expre...
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主要な著者: | , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Public Library of Science
2014
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4134224/ https://ncbi.nlm.nih.gov/pubmed/25126750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104743 |
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