Inherited variation in the ATP-binding cassette transporter ABCB1 and survival after chemotherapy for stage III-IV lung cancer

BACKGROUND: The ATP-binding cassette transporter gene ABCB1 and the glutathione S-transferase gene GSTP1 code for a multidrug resistance (MDR) protein and for a detoxifying phase II metabolic enzyme, respectively, with substrate specificities that include chemotherapy drugs commonly used to treat lu...

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Hlavní autoři: Weissfeld, Joel L., Diergaarde, Brenda, Nukui, Tomoko, Buch, Shama, Pennathur, Arjun, Socinski, Mark A., Siegfried, Jill M., Romkes, Marjorie
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134100/
https://ncbi.nlm.nih.gov/pubmed/25122423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000262
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