Effects of ERCC2 Lys751Gln (A35931C) and CCND1 (G870A) polymorphism on outcome of advanced-stage squamous cell carcinoma of the head and neck are treatment dependent

BACKGROUND: Germline variation in DNA damage response may explain variable treatment outcomes from squamous cell carcinoma of the head and neck (SCCHN). Grouping patients according to stage and radiation treatment, we compared SCCHN survival according to ERCC2 A35931C (Lys751Gln, rs13181) and CCND1...

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Main Authors: Zhong, Shilong, Nukui, Tomoko, Buch, Shama, Diergaarde, Brenda, Weissfeld, Lisa A., Grandis, Jennifer, Romkes, Marjorie, Weissfeld, Joel L.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210907/
https://ncbi.nlm.nih.gov/pubmed/21890746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-11-0520
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