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Replication slippage of the thermophilic DNA polymerases B and D from the Euryarchaeota Pyrococcus abyssi

Replication slippage or slipped-strand mispairing involves the misalignment of DNA strands during the replication of repeated DNA sequences, and can lead to genetic rearrangements such as microsatellite instability. Here, we show that PolB and PolD replicative DNA polymerases from the archaeal model...

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Autors principals: Castillo-Lizardo, Melissa, Henneke, Ghislaine, Viguera, Enrique
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134008/
https://ncbi.nlm.nih.gov/pubmed/25177316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00403
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