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Do crystal structures obviate the need for theoretical models of GPCRs for structure based virtual screening
Recent highly expected structural characterizations of agonist-bound and antagonist-bound beta-2 adrenoreceptor (β2AR) by X-ray crystallography have been widely regarded as critical advances to enable more effective structure-based discovery of GPCRs ligands. It appears that this very important deve...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133977/ https://ncbi.nlm.nih.gov/pubmed/22275072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24035 |
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