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Radioprotection of hematopoietic progenitors by low dose amifostine prophylaxis

PURPOSE: Amifostine is a highly efficacious cytoprotectant when administered in vivo at high doses. However, at elevated doses, drug toxicity manifests for general, non-clinical radioprotective purposes. Various strategies have been developed to avoid toxic side-effects: The simplest is reducing the...

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Autori principali: Seed, Thomas M., Inal, Cynthia E., Singh, Vijay K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Informa Healthcare 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133974/
https://ncbi.nlm.nih.gov/pubmed/24597748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09553002.2014.899450
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