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Detection of rare point mutation via allele-specific amplification in emulsion PCR

It is essential to analyze rare mutations in many fields of biomedical research. However, the detection of rare mutations is usually failed due to the interference of predominant wild-type DNA surrounded. Herein we describe a sensitive and facile method of detecting rare point mutation on the basis...

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Библиографические подробности
Главные авторы: Cheng, Changming, Zhou, Yin, Yang, Chao, Chen, Juan, Wang, Jie, Zhang, Jie, Zhao, Guoping
Формат: Artigo
Язык:Inglês
Опубликовано: Korean Society for Biochemistry and Molecular Biology 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133893/
https://ncbi.nlm.nih.gov/pubmed/23710638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2013.46.5.155
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