Detection of rare point mutation via allele-specific amplification in emulsion PCR

It is essential to analyze rare mutations in many fields of biomedical research. However, the detection of rare mutations is usually failed due to the interference of predominant wild-type DNA surrounded. Herein we describe a sensitive and facile method of detecting rare point mutation on the basis...

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Bibliographic Details
Main Authors: Cheng, Changming, Zhou, Yin, Yang, Chao, Chen, Juan, Wang, Jie, Zhang, Jie, Zhao, Guoping
Format: Artigo
Language:Inglês
Published: Korean Society for Biochemistry and Molecular Biology 2013
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133893/
https://ncbi.nlm.nih.gov/pubmed/23710638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2013.46.5.155
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