تحميل...
Enhanced sialylation and in vivo efficacy of recombinant human α-galactosidase through in vitro glycosylation
Human α-galactosidase A (GLA) has been used in enzyme replacement therapy for patients with Fabry disease. We expressed recombinant GLA from Chinese hamster ovary cells with very high productivity. When compared to an approved GLA (agalsidase beta), its size and charge were found to be smaller and m...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Korean Society for Biochemistry and Molecular Biology
2013
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133871/ https://ncbi.nlm.nih.gov/pubmed/23527859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2013.46.3.192 |
| الوسوم: |
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