Mouse models of polycystic kidney disease induced by defects of ciliary proteins

Polycystic kidney disease (PKD) is a common hereditary disorder which is characterized by fluid-filled cysts in the kidney. Mutation in either PKD1, encoding polycystin-1 (PC1), or PKD2, encoding polycystin-2 (PC2), are causative genes of PKD. Recent studies indicate that renal cilia, known as mecha...

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Bibliographic Details
Main Authors: Ko, Je Yeong, Park, Jong Hoon
Format: Artigo
Language:Inglês
Published: Korean Society for Biochemistry and Molecular Biology 2013
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133850/
https://ncbi.nlm.nih.gov/pubmed/23433108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2013.46.2.022
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