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Structure and catalytic mechanism of human protein tyrosine phosphatome

Together with protein tyrosine kinases (PTKs), protein tyrosine phosphatases (PTPs) serve as hallmarks in cellular signal transduction by controlling the reversible phosphorylation of their substrates. The human genome is estimated to encode more than 100 PTPs, which can be divided into eleven sub-g...

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Autori principali: Kim, Seung Jun, Ryu, Seong Eon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133821/
https://ncbi.nlm.nih.gov/pubmed/23261054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2012.45.12.240
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