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Roles of cysteine residues in the inhibition of human glutamate dehydrogenase by palmitoyl-CoA
Human glutamate dehydrogenase isozymes (hGDH1 and hGDH2) have been known to be inhibited by palmitoyl-CoA with a high affinity. In this study, we have performed the cassette mutagenesis at six different Cys residues (Cys59, Cys93, Cys119, Cys201, Cys274, and Cys323) to identify palmitoyl-CoA binding...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Korean Society for Biochemistry and Molecular Biology
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133811/ https://ncbi.nlm.nih.gov/pubmed/23261056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2012.45.12.156 |
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