Roles of cysteine residues in the inhibition of human glutamate dehydrogenase by palmitoyl-CoA

Human glutamate dehydrogenase isozymes (hGDH1 and hGDH2) have been known to be inhibited by palmitoyl-CoA with a high affinity. In this study, we have performed the cassette mutagenesis at six different Cys residues (Cys59, Cys93, Cys119, Cys201, Cys274, and Cys323) to identify palmitoyl-CoA binding...

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Detalhes bibliográficos
Main Authors: Son, Hyo Jeong, Ha, Seung Cheol, Hwang, Eun Young, Kim, Eun-A, Ahn, Jee-Yin, Choi, Soo Young, Cho, Sung-Woo
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133811/
https://ncbi.nlm.nih.gov/pubmed/23261056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2012.45.12.156
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