Regulated expression of human CD4 rescues helper T cell development in mice lacking expression of endogenous CD4.

During T cell development, precursor thymocytes that co-express the CD4 and CD8 glycoproteins give rise to mature progeny expressing one of these molecules to the exclusion of the other. Continued expression of only CD4 is the hallmark of mature helper T cells, whereas cytotoxic T cells express CD8...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Killeen, N, Sawada, S, Littman, D R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413367/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8467804/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05798.x
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