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Power analysis and sample size estimation for sequence-based association studies

Motivation: Statistical methods have been developed to test for complex trait rare variant (RV) associations, in which variants are aggregated across a region, which is typically a gene. Power analysis and sample size estimation for sequence-based RV association studies are challenging because of th...

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Bibliografiske detaljer
Main Authors: Wang, Gao T., Li, Biao, Lyn Santos-Cortez, Regie P., Peng, Bo, Leal, Suzanne M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133582/
https://ncbi.nlm.nih.gov/pubmed/24778108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu296
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