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The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo
Recombinant activated human factor VII (rhFVIIa) is an established hemostatic agent in hemophilia, but its mechanism of action remains unclear. Although tissue factor (TF) is its natural receptor, rhFVIIa also interacts with the endothelial protein C receptor (EPCR) through its γ-carboxyglutamic aci...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133488/ https://ncbi.nlm.nih.gov/pubmed/24957146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-567297 |
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