Inhibition of the TRAIL Death Receptor by CMV Reveals Its Importance in NK Cell-Mediated Antiviral Defense

TNF-related apoptosis inducing ligand (TRAIL) death receptors (DR) regulate apoptosis and inflammation, but their role in antiviral defense is poorly understood. Cytomegaloviruses (CMV) encode many immune-modulatory genes that shape host immunity, and they utilize multiple strategies to target the T...

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Main Authors: Verma, Shilpi, Loewendorf, Andrea, Wang, Qiao, McDonald, Bryan, Redwood, Alec, Benedict, Chris A.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133390/
https://ncbi.nlm.nih.gov/pubmed/25122141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004268
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