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Lymphoid-Tissue Stromal Cells Coordinate Innate Defense to Cytomegalovirus

During mouse cytomegalovirus (MCMV) infection, the first wave of type I interferon (IFN-I) production peaks at ∼8 h. This IFN-I emanates from splenic stromal cells located in the marginal zone (MZ) and requires B cells that express lymphotoxin. The amount of IFN-I produced at these initial times is...

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Detalhes bibliográficos
Main Authors: Verma, Shilpi, Wang, Qiao, Chodaczek, Grzegorz, Benedict, Chris A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648091/
https://ncbi.nlm.nih.gov/pubmed/23536654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00113-13
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