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A Shift in the Role of Glutamatergic Signaling in the Nucleus Accumbens Core with the Development of an Addicted Phenotype

BACKGROUND: While dopamine signaling in the nucleus accumbens (NAc) plays a well-established role in motivating cocaine use in early “non-addicted” stages, recent evidence suggests that other signaling pathways may be critical once addiction has developed. Given the importance of glutamatergic signa...

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Main Authors: Doyle, Susan E., Ramôa, Carolina, Garber, Garrett, Newman, Joshua, Toor, Shaun, Lynch, Wendy J.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133320/
https://ncbi.nlm.nih.gov/pubmed/24629536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.02.005
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