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Diminished Role of Dopamine D1-Receptor Signaling with the Development of An Addicted Phenotype in Rats

BACKGROUND: While considerable evidence implicates DA D1-receptor signaling in the nucleus accumbens in motivation for cocaine during early stages of addiction, less is known regarding its role following the development of addiction. Here, we examined its role in the development of an addicted pheno...

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Autori principali: Ramôa, Carolina P., Doyle, Susan E., Lycas, Matthew D., Chernau, Andrea K., Lynch, Wendy J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976474/
https://ncbi.nlm.nih.gov/pubmed/24199666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2013.09.028
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