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DNA torsion as a feedback mediator of transcription and chromatin dynamics
The double helical structure of DNA lends itself to topological constraints. Many DNA-based processes alter the topological state of DNA, generating torsional stress, which is efficiently relieved by topoisomerases. Maintaining this topological balance is crucial to cell survival, as excessive torsi...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133216/ https://ncbi.nlm.nih.gov/pubmed/24819949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.29086 |
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