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Analysis of gene expression in mouse preimplantation embryos demonstrates that the primary role of enhancers is to relieve repression of promoters.

Enhancers are generally viewed simply as extensions of promoters, lacking a function of their own. However, previous studies of mouse preimplantation embryos revealed that 1-cell embryos can utilize enhancer-responsive promoters efficiently without an enhancer, whereas 2-cell embryos require an enha...

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Bibliografski detalji
Izdano u:EMBO J
Glavni autori: Majumder, S, Miranda, M, DePamphilis, M L
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1993
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413314/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8458327/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05754.x
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