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Analysis of gene expression in mouse preimplantation embryos demonstrates that the primary role of enhancers is to relieve repression of promoters.

Enhancers are generally viewed simply as extensions of promoters, lacking a function of their own. However, previous studies of mouse preimplantation embryos revealed that 1-cell embryos can utilize enhancer-responsive promoters efficiently without an enhancer, whereas 2-cell embryos require an enha...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Majumder, S, Miranda, M, DePamphilis, M L
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC413314/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8458327/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1993.tb05754.x
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