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A human RNase E-like activity that cleaves RNA sequences involved in mRNA stability control.

We have detected an endoribonucleolytic activity in human cell extracts that processes the Escherichia coli 9S RNA and outer membrane protein A (ompA) mRNA with the same specificity as RNase E from E. coli. The human enzyme was partially purified by ion-exchange chromatography, and the active fracti...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Wennborg, A, Sohlberg, B, Angerer, D, Klein, G, von Gabain, A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41331/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7638189/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.16.7322
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