Histone Modifications and DNA Double-Strand Break Repair after Exposure to Ionizing Radiations

Ionizing radiation exposure induces highly lethal DNA double-strand breaks (DSBs) in all phases of the cell cycle. After DSBs are detected by the cellular machinery, these breaks are repaired by either of two mechanisms: (1) nonhomologous end joining (NHEJ), which re-ligates the broken ends of the D...

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Main Authors: Hunt, Clayton R., Ramnarain, Deepti, Horikoshi, Nobuo, Iyengar, Puneeth, Pandita, Raj K., Shay, Jerry W., Pandita, Tej K.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133051/
https://ncbi.nlm.nih.gov/pubmed/23373901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR3308.2
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