UV-induced activation of AP-1 involves obligatory extranuclear steps including Raf-1 kinase.

Irradiation of cells with ultraviolet light (UV) leads to modifications of c-Jun resembling those elicited by phorbol esters or oncogenes, and to enhanced transcription of AP-1-dependent genes. The UV-induced signal also triggers activation of Raf-1 and MAP-2 kinases. A dominant-negative Raf-1 kinas...

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Detalhes bibliográficos
Main Authors: Radler-Pohl, A, Sachsenmaier, C, Gebel, S, Auer, H P, Bruder, J T, Rapp, U, Angel, P, Rahmsdorf, H J, Herrlich, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC413301/
https://ncbi.nlm.nih.gov/pubmed/8384549
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