Interference between pathway-specific transcription factors: glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo.

Phorbol esters stimulate and glucocorticoid hormones down-regulate a variety of promoters such as that of the collagenase gene through the transcription factor AP-1 (Fos/Jun). We now show by genomic footprinting of the collagenase promoter that phorbol ester treatment of cells results in the binding...

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Publicado en:EMBO J
Autores principales: König, H, Ponta, H, Rahmsdorf, H J, Herrlich, P
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1992
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556691/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1318196/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05283.x
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