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Evaluation of a Luciferase-based Reporter Assay as a Screen for Inhibitors of Estrogen-ERα-induced Proliferation of Breast Cancer Cells

Estrogens, acting through estrogen receptor α (ERα), stimulate breast cancer proliferation, making ERα an attractive drug target. Since 384-well format screens for inhibitors of proliferation can be challenging for some cells, inhibition of luciferase-based reporters is often used as a surrogate end...

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Bibliografski detalji
Glavni autori: Andruska, Neal, Mao, Chengjian, Cherian, Mathew, Zhang, Chen, Shapiro, David J.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132978/
https://ncbi.nlm.nih.gov/pubmed/22498909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057112442960
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