Nalaganje...
Structure of Amantadine-Bound M2 Transmembrane Peptide of Influenza A in Lipid Bilayers from Magic-Angle-Spinning Solid-State NMR: the Role of Ser(31) in Amantadine Binding
The M2 proton channel of influenza A is the target of the antiviral drugs amantadine and rimantadine, whose effectiveness has been abolished by a single-site mutation of Ser(31) to Asn in the transmembrane domain of the protein. Recent high-resolution structures of the M2 transmembrane domain obtain...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4132896/ https://ncbi.nlm.nih.gov/pubmed/19061899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.11.022 |
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