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Junctional Cleft [Ca(2+)](i) Measurements using Novel Cleft-Targeted Ca(2+) Sensors
RATIONALE: Intracellular Ca(2+) concentration ([Ca(2+)](i)) is regulated and signals differently in various subcellular microdomains, which greatly enhances its second messenger versatility. In the heart, sarcoplasmic reticulum (SR) Ca(2+) release and signaling is controlled by local [Ca(2+)](i) in...
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2014
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4132890/ https://ncbi.nlm.nih.gov/pubmed/24871564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.303582 |
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