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Junctional Cleft [Ca(2+)](i) Measurements using Novel Cleft-Targeted Ca(2+) Sensors

RATIONALE: Intracellular Ca(2+) concentration ([Ca(2+)](i)) is regulated and signals differently in various subcellular microdomains, which greatly enhances its second messenger versatility. In the heart, sarcoplasmic reticulum (SR) Ca(2+) release and signaling is controlled by local [Ca(2+)](i) in...

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Bibliographic Details
Main Authors: Despa, Sanda, Shui, Bo, Bossuyt, Julie, Lang, Di, Kotlikoff, Michael I., Bers, Donald M.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132890/
https://ncbi.nlm.nih.gov/pubmed/24871564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.303582
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