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Inflammatory Mechanisms in sepsis: Elevated Invariant Natural Killer T-cell numbers in mouse and their modulatory effect on Macrophage function

Invariant Natural Killer T-cells (iNKT) cells are emerging as key mediators of innate immune cellular and inflammatory responses to sepsis and peritonitis. iNKT-cells mediate survival following murine septic shock. Macrophages are pivotal to survival following sepsis. iNKT-cells have been shown to m...

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Detalhes bibliográficos
Main Authors: Heffernan, Daithi S., Monaghan, Sean F., Thakkar, Rajan K., Tran, Mai L., Chung, Chun-Shiang, Gregory, Stephen H., Cioffi, William G., Ayala, Alfred
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132843/
https://ncbi.nlm.nih.gov/pubmed/23807244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e31829ca519
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