Cargando...
Pontine Norepinephrine Defects in Mecp2-null Mice Involve Deficient Expression of Dopamine β-hydroxylase but not a Loss of Catecholaminergic Neurons
Rett syndrome is a neurodevelopmental disorder caused by Mecp2 gene mutations. In RTT patients and Mecp2-null (Mecp2(−/Y)) mice, norepinephrine (NE) content drops significantly, which may play a role in breathing arrhythmia, sleep disorders and sudden death in RTT. However, the underlying mechanisms...
Gardado en:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4132834/ https://ncbi.nlm.nih.gov/pubmed/20193660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.02.156 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|