Histone Cross-talk Connects Protein Phosphatase 1α (PP1α) and Histone Deacetylase (HDAC) Pathways to Regulate the Functional Transition of Bromodomain-containing 4 (BRD4) for Inducible Gene Expression

Transcription elongation has been recognized as a rate-limiting step for the expression of signal-inducible genes. Through recruitment of positive transcription elongation factor P-TEFb, the bromodomain-containing protein BRD4 plays critical roles in regulating the transcription elongation of a vast...

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Hlavní autoři: Hu, Xiangming, Lu, Xiaodong, Liu, Runzhong, Ai, Nanping, Cao, Zhenhua, Li, Yannan, Liu, Jiangfang, Yu, Bin, Liu, Kai, Wang, Huiping, Zhou, Chao, Wang, Yu, Han, Aidong, Ding, Feng, Chen, Ruichuan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132813/
https://ncbi.nlm.nih.gov/pubmed/24939842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.570812
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