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A Novel Interaction between the SH2 Domain of Signaling Adaptor Protein Nck-1 and the Upstream Regulator of the Rho Family GTPase Rac1 Engulfment and Cell Motility 1 (ELMO1) Promotes Rac1 Activation and Cell Motility

Nck family proteins function as adaptors to couple tyrosine phosphorylation signals to actin cytoskeleton reorganization. Several lines of evidence indicate that Nck family proteins involve in regulating the activity of Rho family GTPases. In the present study, we characterized a novel interaction b...

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Hlavní autoři: Zhang, Guo, Chen, Xia, Qiu, Fanghua, Zhu, Fengxin, Lei, Wenjing, Nie, Jing
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132809/
https://ncbi.nlm.nih.gov/pubmed/24928514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.549550
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