SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility

The coordination of the several pathways involved in cell motility is poorly understood. Here, we identify SH3BP1, belonging to the RhoGAP family, as a partner of the exocyst complex, and establish a physical and functional link between two motility-driving pathways, the Ral/exocyst and Rac signalin...

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Hlavní autoři: Parrini, Maria Carla, Sadou-Dubourgnoux, Amel, Aoki, Kazuhiro, Kunida, Katsuyuki, Biondini, Marco, Hatzoglou, Anastassia, Poullet, Patrick, Formstecher, Etienne, Yeaman, Charles, Matsuda, Michiyuki, Rossé, Carine, Camonis, Jacques
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488376/
https://ncbi.nlm.nih.gov/pubmed/21658605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.03.032
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