SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility

The coordination of the several pathways involved in cell motility is poorly understood. Here, we identify SH3BP1, belonging to the RhoGAP family, as a partner of the exocyst complex, and establish a physical and functional link between two motility-driving pathways, the Ral/exocyst and Rac signalin...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Parrini, Maria Carla, Sadou-Dubourgnoux, Amel, Aoki, Kazuhiro, Kunida, Katsuyuki, Biondini, Marco, Hatzoglou, Anastassia, Poullet, Patrick, Formstecher, Etienne, Yeaman, Charles, Matsuda, Michiyuki, Rossé, Carine, Camonis, Jacques
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488376/
https://ncbi.nlm.nih.gov/pubmed/21658605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.03.032
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk