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Unique Properties of Human β-Defensin 6 (hBD6) and Glycosaminoglycan Complex: SANDWICH-LIKE DIMERIZATION AND COMPETITION WITH THE CHEMOKINE RECEPTOR 2 (CCR2) BINDING SITE

Defensins are components of the innate immune system that promote the directional migration and activation of dendritic cells, thereby modulating the adaptive immune response. Because matrix glycosaminoglycan (GAG) is known to be important for these functions, we characterized the structural feature...

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書誌詳細
主要な著者: De Paula, Viviane S., Pomin, Vitor H., Valente, Ana Paula
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132797/
https://ncbi.nlm.nih.gov/pubmed/24970887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.572529
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