The expression of the β-defensins hBD-2 and hBD-3 is differentially regulated by NF-κB and MAPK/AP-1 pathways in an in vitro model of Candida esophagitis

BACKGROUND: Candida albicans resides on epithelial surfaces as part of the physiological microflora. However, under certain conditions it may cause life-threatening infections like Candida sepsis. Human β-defensins (hBDs) are critical components of host defense at mucosal surfaces and we have recent...

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Hauptverfasser: Steubesand, Nadine, Kiehne, Karlheinz, Brunke, Gabriele, Pahl, Rene, Reiss, Karina, Herzig, Karl-Heinz, Schubert, Sabine, Schreiber, Stefan, Fölsch, Ulrich R, Rosenstiel, Philip, Arlt, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702365/
https://ncbi.nlm.nih.gov/pubmed/19523197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-10-36
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