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Phospholipase D and the Maintenance of Phosphatidic Acid Levels for Regulation of Mammalian Target of Rapamycin (mTOR)

Phosphatidic acid (PA) is a critical metabolite at the heart of membrane phospholipid biosynthesis. However, PA also serves as a critical lipid second messenger that regulates several proteins implicated in the control of cell cycle progression and cell growth. Three major metabolic pathways generat...

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Detalhes bibliográficos
Main Authors: Foster, David A., Salloum, Darin, Menon, Deepak, Frias, Maria A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132766/
https://ncbi.nlm.nih.gov/pubmed/24990952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.566091
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