DNA bridging and looping by HMO1 provides a mechanism for stabilizing nucleosome-free chromatin

The regulation of chromatin structure in eukaryotic cells involves abundant architectural factors such as high mobility group B (HMGB) proteins. It is not understood how these factors control the interplay between genome accessibility and compaction. In vivo, HMO1 binds the promoter and coding regio...

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Библиографические подробности
Главные авторы: Murugesapillai, Divakaran, McCauley, Micah J., Huo, Ran, Nelson Holte, Molly H., Stepanyants, Armen, Maher, L. James, Israeloff, Nathan E., Williams, Mark C.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2014
Предметы:
Gene regulation, Chromatin and Epigenetics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132745/
https://ncbi.nlm.nih.gov/pubmed/25063301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku635
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