Genome-wide analysis of genetic and epigenetic control of programmed DNA deletion

During the development of the somatic genome from the Paramecium germline genome the bulk of the copies of ∼45 000 unique, internal eliminated sequences (IESs) are deleted. IES targeting is facilitated by two small RNA (sRNA) classes: scnRNAs, which relay epigenetic information from the parental nuc...

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Main Authors: Swart, Estienne C., Wilkes, Cyril Denby, Sandoval, Pamela Y., Arambasic, Miroslav, Sperling, Linda, Nowacki, Mariusz
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132734/
https://ncbi.nlm.nih.gov/pubmed/25016527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku619
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