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Crystal structure of RNase H3–substrate complex reveals parallel evolution of RNA/DNA hybrid recognition
RNases H participate in the replication and maintenance of genomic DNA. RNase H1 cleaves the RNA strand of RNA/DNA hybrids, and RNase H2 in addition hydrolyzes the RNA residue of RNA–DNA junctions. RNase H3 is structurally closely related to RNases H2, but its biochemical properties are similar to t...
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| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4132731/ https://ncbi.nlm.nih.gov/pubmed/25016521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku615 |
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